2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Melatonin Receptor
  5. Melatonin Receptor Inhibitors

Melatonin Receptor Inhibitors

MT1

MT2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Melatonin Receptor Agonists & Antagonists
Product Name MT1 MT2 Purity
Ramelteon
MT1
MT2
99.87%
Luzindole  
MT2
99.62%
4-P-PDOT  
MT2
99.80%
8-M-PDOT  
MT2
99.54%
Tasimelteon  
MT2
99.68%
Agomelatine-d6
MT1
MT2
98.57%
ACH-000143
MT1, EC50: 0.06 nM
MT2, EC50: 0.32 nM
98.58%
S-22153
MT1, EC50: 19 nM
MT2, EC50: 4.6 nM
99.85%
UCM 608
MT1
MT2
99.18%
Agomelatine-d4
MT1
MT2
Melatonin receptor agonist 1
MT1, Ki: 1140 nM
MT2, Ki: 108 nM
Ramelteon-d5
MT1
MT2
Agomelatin-d3
MT1
MT2
≥98.0%
DH97
MT1, pKi: 6.08
MT2, pKi: 8.03
6-Chloromelatonin
MT1, pKi: 8.9
MT2, pKi: 9.1
Tasimelteon-d5  
MT2